Eric S. Lander

OpenAlex profile · ORCID

Selected research works

Up to 100 selected research works. Source updated 2026-10-27T18:58:15+00:00.

1. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles · 2005 · 53,554 citations
2. Initial sequencing and analysis of the human genome · 2001 · 24,204 citations
3. A global reference for human genetic variation · 2015 · 18,219 citations
4. Integrative genomics viewer · 2011 · 15,372 citations
5. Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring · 1999 · 11,516 citations
6. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes · 2003 · 10,173 citations
7. A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping · 2014 · 9,203 citations
8. Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome · 2009 · 8,885 citations
9. A map of human genome variation from population-scale sequencing · 2010 · 7,879 citations
10. Comprehensive genomic characterization defines human glioblastoma genes and core pathways · 2008 · 7,723 citations
11. An integrated map of genetic variation from 1,092 human genomes · 2012 · 7,709 citations
12. Initial sequencing and comparative analysis of the mouse genome · 2002 · 7,179 citations
13. MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations · 1987 · 6,657 citations
14. Comprehensive molecular characterization of gastric adenocarcinoma · 2014 · 6,485 citations
15. The International HapMap Project · 2003 · 6,057 citations
16. The Structure of Haplotype Blocks in the Human Genome · 2002 · 5,863 citations
17. Development and Applications of CRISPR-Cas9 for Genome Engineering · 2014 · 5,755 citations
18. Comprehensive molecular profiling of lung adenocarcinoma · 2014 · 5,717 citations
19. Mutational heterogeneity in cancer and the search for new cancer-associated genes · 2013 · 5,458 citations
20. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells · 2006 · 5,359 citations
21. The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease · 2006 · 5,245 citations
22. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results · 1995 · 5,241 citations
23. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. · 1989 · 5,235 citations
24. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project · 2007 · 5,225 citations
25. The Somatic Genomic Landscape of Glioblastoma · 2013 · 5,008 citations
26. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples · 2013 · 4,994 citations
27. A Draft Sequence of the Neandertal Genome · 2010 · 4,315 citations
28. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells · 2007 · 4,127 citations
29. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals · 2009 · 4,099 citations
30. The landscape of somatic copy-number alteration across human cancers · 2010 · 4,010 citations
31. Comprehensive genomic characterization of squamous cell lung cancers · 2012 · 3,976 citations
32. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 · 2009 · 3,908 citations
33. Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments · 2016 · 3,857 citations
34. Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence · 2014 · 3,527 citations
35. The repertoire of mutational signatures in human cancer · 2020 · 3,492 citations
36. Comprehensive molecular characterization of clear cell renal cell carcinoma · 2013 · 3,477 citations
37. Genetic Dissection of Complex Traits · 1994 · 3,420 citations
38. Detecting Novel Associations in Large Data Sets · 2011 · 3,358 citations
39. Genomic Classification of Cutaneous Melanoma · 2015 · 3,145 citations
40. The Molecular Taxonomy of Primary Prostate Cancer · 2015 · 3,118 citations
41. Discovery and saturation analysis of cancer genes across 21 tumour types · 2014 · 3,092 citations
42. Integrated Genomic Characterization of Papillary Thyroid Carcinoma · 2014 · 3,072 citations
43. Pan-cancer analysis of whole genomes · 2020 · 3,064 citations
44. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms · 2001 · 2,975 citations
45. Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations · 2018 · 2,952 citations
46. An immunogenic personal neoantigen vaccine for patients with melanoma · 2017 · 2,929 citations
47. Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation · 1999 · 2,924 citations
48. Parametric and nonparametric linkage analysis: a unified multipoint approach. · 1996 · 2,883 citations
49. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression · 2009 · 2,873 citations
50. Genetic Screens in Human Cells Using the CRISPR-Cas9 System · 2013 · 2,853 citations