Natalie A. Sims

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ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

1. Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

   2010 · 804 citations

2. Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit

   2014 · 709 citations

3. Osteoclast-derived activity in the coupling of bone formation to resorption

   2005 · 659 citations

4. Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption

   2008 · 510 citations

5. Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment

   2007 · 424 citations

6. Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

   2001 · 388 citations

7. Osteoprotegerin Reduces Osteoclast Numbers and Prevents Bone Erosion in Collagen-Induced Arthritis

   2002 · 368 citations

8. Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males

   2002 · 353 citations

9. Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis

   2000 · 339 citations

10. The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

    2009 · 330 citations

11. Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice

    2010 · 300 citations

12. Quantifying the osteocyte network in the human skeleton

    2015 · 299 citations

13. Model structure and control of bone remodeling: A theoretical study

    2008 · 298 citations

14. Decreased C-Src Expression Enhances Osteoblast Differentiation and Bone Formation

    2000 · 284 citations

15. Osteoclasts Provide Coupling Signals to Osteoblast Lineage Cells Through Multiple Mechanisms

    2019 · 282 citations

16. Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

    2009 · 272 citations

17. Interleukin‐6 modulates production of T lymphocyte–derived cytokines in antigen‐induced arthritis and drives inflammation‐induced osteoclastogenesis

    2005 · 270 citations

18. Bone homeostasis in growth hormone receptor–null mice is restored by IGF-I but independent of Stat5

    2000 · 251 citations

19. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan

    2024 · 236 citations

20. Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice

    2007 · 226 citations

21. RANKL/OPG; Critical role in bone physiology

    2015 · 211 citations

22. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

    2004 · 208 citations

23. A functional androgen receptor is not sufficient to allow estradiol to protect bone after gonadectomy in estradiol receptor–deficient mice

    2003 · 199 citations

24. EphrinB2 Regulation by PTH and PTHrP Revealed by Molecular Profiling in Differentiating Osteoblasts

    2008 · 198 citations

25. Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways

    2004 · 194 citations

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