RESEARCHER PROFILE

Denis J. Wakeham

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D

Cardiff Metropolitan University

Cardiovascular and exercise physiologyCardiovascular Function and Risk FactorsHeart Failure Treatment and ManagementCardiovascular Health and Disease PreventionHeart Rate Variability and Autonomic Control

Denis J. Wakeham works in Cardiovascular and exercise physiology, Cardiovascular Function and Risk Factors, Heart Failure Treatment and Management, Cardiovascular Health and Disease Prevention, Heart Rate Variability and Autonomic Control. Recorded institutional associations include Texas Health Dallas, Institute for Exercise and Environmental Medicine, Cardiff Metropolitan University.

95Publications
537Citations
11H-index

ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

  1. Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia

    2017 · 93 citations

  2. Challenging the Hemodynamic Hypothesis in Heart Failure With Preserved Ejection Fraction: Is Exercise Capacity Limited by Elevated Pulmonary Capillary Wedge Pressure?

    2022 · 60 citations

  3. Acute intermittent hypercapnic hypoxia and sympathetic neurovascular transduction in men

    2019 · 50 citations

  4. Cardiac Effects of Long-Duration Space Flight

    2023 · 50 citations

  5. Nitric oxide contributes to cerebrovascular shear‐mediated dilatation but not steady‐state cerebrovascular reactivity to carbon dioxide

    2021 · 39 citations

  6. Total haemoglobin mass, but not haemoglobin concentration, is associated with preoperative cardiopulmonary exercise testing-derived oxygen-consumption variables

    2016 · 29 citations

  7. Distinct contributions of skin and core temperatures to flow-mediated dilation of the brachial artery following passive heating

    2020 · 26 citations

  8. Identifying the Mechanisms of a Peripherally Limited Exercise Phenotype in Patients With Heart Failure With Preserved Ejection Fraction

    2024 · 22 citations

  9. Reducing Pulmonary Capillary Wedge Pressure During Exercise Exacerbates Exertional Dyspnea in Patients With Heart Failure With Preserved Ejection Fraction

    2023 · 19 citations

  10. The influence of habitual endurance exercise on carotid artery strain and strain rate in young and middle‐aged men

    2020 · 13 citations

  11. Excess Pericardial Fat Is Related to Adverse Cardio-Mechanical Interaction in Heart Failure With Preserved Ejection Fraction

    2023 · 13 citations

  12. Carotid artery wall mechanics in young males with high cardiorespiratory fitness

    2018 · 11 citations

  13. Heart-Lung Interactions in HFpEF

    2025 · 11 citations

  14. Upward resetting of the vascular sympathetic baroreflex in middle-aged male runners

    2019 · 10 citations

  15. The influence of barosensory vessel mechanics on the vascular sympathetic baroreflex: insights into aging and blood pressure homeostasis

    2020 · 8 citations

  16. Effects of Synchronizing Foot Strike and Cardiac Phase on Exercise Hemodynamics in Patients With Cardiac Resynchronization Therapy: A Within-Subjects Pilot Study to Fine-Tune Cardio-Locomotor Coupling for Heart Failure

    2023 · 8 citations

  17. Aortic stiffness contributes to greater pressor responses during static hand grip exercise in healthy young and middle-aged normotensive men

    2023 · 7 citations

  18. Pulmonary gas exchange in relation to exercise pulmonary hypertension in patients with heart failure with preserved ejection fraction

    2024 · 7 citations

  19. Effect of Acute Resistance Exercise and Resistance Exercise Training on Central Pulsatile Hemodynamics and Large Artery Stiffness: Part II

    2025 · 6 citations

  20. Distinct Blood Volume and Left Ventricular Adaptation to Severe Obesity in Middle-Aged Adults at Risk for Heart Failure

    2025 · 6 citations

  21. Impaired longitudinal systolic–diastolic coupling and cardiac response to exercise in patients with hypertrophic cardiomyopathy

    2024 · 4 citations

  22. Effect of Acute Resistance Exercise and Resistance Exercise Training on Central Pulsatile Hemodynamics and Large Artery Stiffness: Part I

    2025 · 4 citations

  23. Functional sympatholysis of neuropeptide Y‐mediated vasoconstriction in humans

    2025 · 4 citations

  24. Impaired exercise hemodynamic responses in patients with HFpEF without a sympathetic vasoconstrictor reserve

    2025 · 4 citations

  25. Microvascular Function and Ambulatory Capacity in Peripheral Artery Disease

    2025 · 4 citations

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