Ashraf Said Al Madhoun

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ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

1. The Tale of Two Domains

   2007 · 199 citations

2. Could the D614G substitution in the SARS-CoV-2 spike (S) protein be associated with higher COVID-19 mortality?

   2020 · 145 citations

3. Role of Caveolin-1 in Diabetes and Its Complications

   2020 · 124 citations

4. Short Sleep Duration and Its Association with Obesity and Other Metabolic Risk Factors in Kuwaiti Urban Adults

   2021 · 117 citations

5. Functional Dissection of the NuA4 Histone Acetyltransferase Reveals Its Role as a Genetic Hub and that Eaf1 Is Essential for Complex Integrity

   2008 · 114 citations

6. Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways

   2023 · 111 citations

7. HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage

   2006 · 105 citations

8. ROS/TNF-α Crosstalk Triggers the Expression of IL-8 and MCP-1 in Human Monocytic THP-1 Cells via the NF-κB and ERK1/2 Mediated Signaling

   2021 · 89 citations

9. PKD1 Duplicated regions limit clinical Utility of Whole Exome Sequencing for Genetic Diagnosis of Autosomal Dominant Polycystic Kidney Disease

   2019 · 89 citations

10. Increased Expression of Meteorin-Like Hormone in Type 2 Diabetes and Obesity and Its Association with Irisin

    2019 · 82 citations

11. Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance

    2020 · 81 citations

12. Wharton’s jelly mesenchymal stem cells: a concise review of their secretome and prospective clinical applications

    2023 · 80 citations

13. Boron-Containing Nucleosides as Potential Delivery Agents for Neutron Capture Therapy of Brain Tumors

    2004 · 79 citations

14. Dental Pulp Stem Cells Derived From Adult Human Third Molar Tooth: A Brief Review

    2021 · 78 citations

15. Oxidative Stress Induces Expression of the Toll-Like Receptors (TLRs) 2 and 4 in the Human Peripheral Blood Mononuclear Cells: Implications for Metabolic Inflammation

    2019 · 73 citations

16. Evaluation of Human Thymidine Kinase 1 Substrates as New Candidates for Boron Neutron Capture Therapy

    2004 · 70 citations

17. The Role of Thymidine Kinases in the Activation of Pyrimidine Nucleoside Analogues

    2004 · 69 citations

18. Synthesis and Biological Evaluation of Neutral and Zwitterionic 3-Carboranyl Thymidine Analogues for Boron Neutron Capture Therapy

    2005 · 66 citations

19. Multi-Lineage Differentiation of Human Umbilical Cord Wharton’s Jelly Mesenchymal Stromal Cells Mediates Changes in the Expression Profile of Stemness Markers

    2015 · 65 citations

20. SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains

    2021 · 63 citations

21. Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway

    2020 · 62 citations

22. IL-1β and TNFα Cooperativity in Regulating IL-6 Expression in Adipocytes Depends on CREB Binding and H3K14 Acetylation

    2021 · 60 citations

23. MAP kinase phosphatase DUSP1 is overexpressed in obese humans and modulated by physical exercise

    2014 · 60 citations

24. Hedgehog Signaling Regulates MyoD Expression and Activity

    2012 · 58 citations

25. Synthesis of a Small Library of 3-(Carboranylalkyl)thymidines and Their Biological Evaluation as Substrates for Human Thymidine Kinases 1 and 2

    2002 · 58 citations

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