RESEARCHER PROFILE
Christian Frech
← Back to Technische Hochschule Mannheim
C
Technische Hochschule Mannheim
Christian Frech works in Protein purification and stability, Analytical Chemistry and Chromatography, Monoclonal and Polyclonal Antibodies Research, Genomics and Phylogenetic Studies, Neurofibromatosis and Schwannoma Cases. Recorded institutional associations include Technische Hochschule Mannheim.
79Publications
2,764Citations
26H-index
Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.
Selected research works
Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.
Mutational landscape of intrahepatic cholangiocarcinoma
2014 · 434 citationsGenome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling
2013 · 329 citationsConservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
2021 · 188 citationsKRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia
2015 · 126 citationsComprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment
2021 · 106 citationsProteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype
2016 · 96 citationsVariant surface antigens of malaria parasites: functional and evolutionary insights from comparative gene family classification and analysis
2013 · 82 citationsSchwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8
2021 · 80 citationsModeling of salt and pH gradient elution in ion‐exchange chromatography
2013 · 72 citationsGenome Comparison of Human and Non-Human Malaria Parasites Reveals Species Subset-Specific Genes Potentially Linked to Human Disease
2011 · 65 citationsSystematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
2020 · 62 citationsPreferential binding of an unfolded protein to DsbA.
1996 · 60 citationsCation-exchange chromatography of monoclonal antibodies: Characterisation of a novel stationary phase designed for production-scale purification
2010 · 57 citationsGenomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia
2016 · 55 citationsGenome-wide variations in a natural isolate of the nematode Caenorhabditis elegans
2014 · 52 citationsWhole-genome sequencing of Mesorhizobium huakuii 7653R provides molecular insights into host specificity and symbiosis island dynamics
2014 · 52 citationsUltra-High Density SNParray in Neuroblastoma Molecular Diagnostics
2014 · 47 citationsApplication of linear pH gradients for the modeling of ion exchange chromatography: Separation of monoclonal antibody monomer from aggregates
2015 · 42 citationsThe Vibrio Cholerae Type VI Secretion System: Evaluating its Role in the Human Disease Cholera
2010 · 41 citationsNeuroblastoma cells undergo transcriptomic alterations upon dissemination into the bone marrow and subsequent tumor progression
2017 · 40 citationsCooVar: Co-occurring variant analyzer
2012 · 35 citationsOrthoClusterDB: an online platform for synteny blocks
2009 · 33 citationsGenome-Wide Comparative Gene Family Classification
2010 · 30 citationsEvaluation of differences between dual salt‐pH gradient elution and mono gradient elution using a thermodynamic model: Simultaneous separation of six monoclonal antibody charge and size variants on preparative‐scale ion exchange chromatographic resin
2018 · 28 citationsInfluence of surface modification on protein retention in ion-exchange chromatography
2008 · 26 citations