RESEARCHER PROFILE

Adam Penn‐Nicholson

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A

Institute of Infectious Disease and Molecular Medicine

Tuberculosis Research and EpidemiologyInfectious Diseases and TuberculosisDiagnosis and treatment of tuberculosisImmune responses and vaccinationsMycobacterium research and diagnosis

Adam Penn‐Nicholson works in Tuberculosis Research and Epidemiology, Infectious Diseases and Tuberculosis, Diagnosis and treatment of tuberculosis, Immune responses and vaccinations, Mycobacterium research and diagnosis. Recorded institutional associations include FIND, University of Cape Town, South African Tuberculosis Vaccine Initiative.

143Publications
5,897Citations
36H-index

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

  1. A blood RNA signature for tuberculosis disease risk: a prospective cohort study

    2016 · 780 citations
  2. T-cell activation is an immune correlate of risk in BCG vaccinated infants

    2016 · 267 citations
  3. Biology of CCR5 and Its Role in HIV Infection and Treatment

    2006 · 266 citations
  4. Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease

    2017 · 251 citations
  5. Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis

    2018 · 251 citations
  6. A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes

    2018 · 243 citations
  7. Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor

    2006 · 214 citations
  8. Comparing the Ex Vivo Fitness of CCR5-Tropic Human Immunodeficiency Virus Type 1 Isolates of Subtypes B and C

    2002 · 202 citations
  9. Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis

    2017 · 179 citations
  10. RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

    2020 · 177 citations
  11. Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise

    2024 · 171 citations
  12. Metabolite changes in blood predict the onset of tuberculosis

    2018 · 156 citations
  13. Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial

    2021 · 154 citations
  14. Safety and immunogenicity of the novel tuberculosis vaccine ID93 + GLA-SE in BCG-vaccinated healthy adults in South Africa: a randomised, double-blind, placebo-controlled phase 1 trial

    2018 · 149 citations
  15. Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting

    2015 · 139 citations
  16. Live-attenuated Mycobacterium tuberculosis vaccine MTBVAC versus BCG in adults and neonates: a randomised controlled, double-blind dose-escalation trial

    2019 · 132 citations
  17. A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis

    2011 · 123 citations
  18. A prospective multicentre diagnostic accuracy study for the Truenat tuberculosis assays

    2021 · 114 citations
  19. Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results

    2021 · 109 citations
  20. T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection

    2023 · 108 citations
  21. Detection of isoniazid, fluoroquinolone, ethionamide, amikacin, kanamycin, and capreomycin resistance by the Xpert MTB/XDR assay: a cross-sectional multicentre diagnostic accuracy study

    2021 · 103 citations
  22. Tests for tuberculosis infection: landscape analysis

    2021 · 101 citations
  23. Safety and immunogenicity of the adjunct therapeutic vaccine ID93 + GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo-controlled, phase 2a trial

    2020 · 99 citations
  24. Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study

    2019 · 97 citations
  25. Performance of diagnostic and predictive host blood transcriptomic signatures for Tuberculosis disease: A systematic review and meta-analysis

    2020 · 75 citations

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