Beston Faiek Nore

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ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

1. Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

   2009 · 516 citations

2. The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species

   2001 · 315 citations

3. Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling

   2005 · 199 citations

4. Mutation Screening of the BTK Gene in 56 Families With X-Linked Agammaglobulinemia (XLA): 47 Unique Mutations Without Correlation to Clinical Course

   1998 · 127 citations

5. Redistribution of Bruton's tyrosine kinase by activation of phosphatidylinositol 3-kinase and Rho-family GTPases

   2000 · 122 citations

6. Nucleocytoplasmic Shuttling of Bruton's Tyrosine Kinase

   2000 · 87 citations

7. Inhibitors of BTK and ITK : State of the New Drugs for Cancer, Autoimmunity and Inflammatory Diseases

   2013 · 77 citations

8. Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-κB

   2008 · 73 citations

9. Glutathione transferase mu 2 protects glioblastoma cells against aminochrome toxicity by preventing autophagy and lysosome dysfunction

   2014 · 70 citations

10. Proton-pumping N,N'-dicyclohexylcarbodiimide-sensitive inorganic: pyrophosphate synthase from Rhodospirillum rubrum: purification, characterization, and reconstitution

    1991 · 69 citations

11. Signalling of Bruton's Tyrosine Kinase, Btk

    1999 · 63 citations

12. Functional Interaction of Caveolin-1 with Bruton's Tyrosine Kinase and Bmx

    2002 · 62 citations

13. Lindvall, J. M. et al. Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling. Immunol. Rev. 203, 200-215

    2005 · 52 citations

14. Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)

    2002 · 52 citations

15. Anti‐leukaemic effects induced by APR‐246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells

    2016 · 49 citations

16. Stable Expression of Short Interfering RNA for DT-Diaphorase Induces Neurotoxicity

    2010 · 49 citations

17. Btk29A Promotes Wnt4 Signaling in the Niche to Terminate Germ Cell Proliferation in Drosophila

    2014 · 47 citations

18. Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases

    2003 · 42 citations

19. Missense mutations affecting a conserved cysteine pair in the TH domain of Btk

    1997 · 41 citations

20. Dual Phosphorylation of Btk by Akt/Protein Kinase B Provides Docking for 14-3-3ζ, Regulates Shuttling, and Attenuates both Tonic and Induced Signaling in B Cells

    2013 · 37 citations

21. Studies on photosynthetic inorganic pyrophosphate formation in Rhodospirillum rubrum chromatophores

    1986 · 37 citations

22. B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing

    2016 · 35 citations

23. Phylogeny of Tec Family Kinases: Identification of a Premetazoan Origin of Btk, Bmx, Itk, Tec, Txk, and the Btk Regulator SH3BP5

    2008 · 35 citations

24. The coupling between protonmotive force and the NAD(P)+transhydrogenase in chromatophores from photosynthetic bacteria

    1989 · 33 citations

25. X-linked agammaglobulinemia: lack of mature B lineage cells caused by mutations in the Btk kinase

    1998 · 31 citations

26. Immunological cross-reactivity between proton-pumping inorganic pyrophosphatases of widely phylogenic separated species

    1991 · 29 citations

27. Regulation of Nucleocytoplasmic Shuttling of Bruton's Tyrosine Kinase (Btk) through a Novel SH3-Dependent Interaction with Ankyrin Repeat Domain 54 (ANKRD54)

    2012 · 28 citations

28. Signaling of the ITK (Interleukin 2-inducible T Cell Kinase)-SYK (Spleen Tyrosine Kinase) Fusion Kinase Is Dependent on Adapter SLP-76 and on the Adapter Function of the Kinases SYK and ZAP70

    2013 · 20 citations

29. A novel missense mutation in the CLCN7 gene linked to benign autosomal dominant osteopetrosis: a case series

    2013 · 18 citations

30. Sporadic incidence of Fascioliasis detected during Hepatobiliary procedures: A study of 18 patients from Sulaimaniyah governorate

    2012 · 17 citations

31. Inducible H1 Promoter-Driven Lentiviral siRNA Expression by Stuffer Reporter Deletion

    2005 · 15 citations

32. Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7

    2016 · 14 citations

33. Phosphatidylinositol-3-kinase-dependent phosphorylation of SLP-76 by the lymphoma-associated ITK-SYK fusion-protein

    2009 · 14 citations

34. Photosynthetic formation of inorganic pyrophosphate in phototrophic bacteria

    1990 · 14 citations

35. Synthesis of pyrophosphate coupled to the reverse energy‐linked transhydrogenase reaction in Rhodospirillum rubrum chromatophores

    1986 · 14 citations

36. Translocation-generated ITK-FER and ITK-SYK fusions induce STAT3 phosphorylation and CD69 expression

    2018 · 12 citations

37. Cytogenetic Response in Chronic Myeloid Leukaemia Patients Treated with Imatinib Mesylate Homolog-Drugs: 6 Year’s Transitional Study

    2014 · 11 citations

38. Hormonal Study of Primary Infertile Women

    2013 · 11 citations

39. Precursor T-cell acute lymphoblastic leukemia presenting with bone marrow necrosis: a case report

    2012 · 10 citations

40. Diethylstilbestrol is a potent inhibitor of the H+-PPase but not of the H+-ATPase of Rhodospirillum rubrum chromatophores

    1987 · 9 citations

41. IoT Aquaculture System for Sea Bass and Giant Freshwater Prawn Farming in Brunei

    2023 · 7 citations

42. Longitudinal plication - a surgical strategy for complete rectal prolapse management

    2014 · 7 citations

43. Antioxidant content following fermentation of lemongrass for herbal beverage development

    2024 · 6 citations

44. Fermented beverages of natural herbs: Cymbopogon citratus, Zingiber officinale, Moringa oleifera, Mentha, and Curcuma longa

    2024 · 6 citations

45. Correlation between Serum Tryptase Level and Disease Severity in Asthmatic Patients in the Sulaimani Governorate

    2016 · 6 citations

46. Non-Invasive Digital Refractometer to Measure Maturation of Climacteric Fruits

    2024 · 4 citations

47. Youth Resilience Toward Climate Smart Agriculture Technology Adoption in Brunei Darussalam

    2024 · 4 citations

48. The Role of Bruton´s Tyrosine Kinase (Btk) in Phosphoinositide-Dependent Signaling

    2000 · 4 citations

49. Inorganic pyrophosphate synthesis after a short light flash in chromatophores from Rhodospirillum rubrum

    1986 · 4 citations

50. BIOACTIVITY CHARACTERIZATION OF PURIFIED RECOMBINANT HYPOTHETICAL PROTEIN CODED BY OPEN READING FRAME-112 OF STREPTOMYCES.

    2021 · 3 citations

51. ANKRD54 preferentially selects Bruton’s Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library

    2017 · 3 citations

52. The impact of palm sugar replacement on physicochemical characteristics of Syzygium Malaccense Jam processing

    2023 · 2 citations

53. Description of hemoglobin H disease mutations in alpha thalassemia patients in Sulaimani Region in Kurdistan Region, Iraq

    2021 · 2 citations

54. EVALUATION OF SERUM IRISIN WITH LIPID PROFILE IN TYPE-2 DIABETIC PATIENTS IN SULAIMANI

    2018 · 2 citations

55. Seroprevalence and Genotypic Distribution Patterns of Hepatitis C Virus among Infected Patients from Erbil Province: Kurdistan/Iraq

    2018 · 2 citations

56. Terminating B cell receptor signaling

    2017 · 2 citations

57. X-linked agammaglobulinemia: lack of mature B lineage cells caused by mutations in the Btk kinase

    1998 · 2 citations

58. Developing Herbal-Based Beverage Fermentation Using Saccharomyces Cerevisiae: The Physico-Chemical Properties

    2024 · 1 citations

59. Food Labelling Practices of Local Products in Brunei Darussalam

    2024 · 1 citations

60. Association of Serum Homocysteine with Controlled and Uncontrolled Type2 Diabetes Mellitus in Sulaimani City

    2022 · 1 citations

61. A SYNTHETIC CELL-PENETRATING PEPTIDE (CPP) WITH PROTAMINE CONJUGATE UTILIZED FOR GENE DELIVERY

    2012 · 1 citations

62. A Synthetic cell-penetrating peptide (CPP) with protamine conjugate utilized for Gene Therapy

    2012 · 1 citations

63. Partial Purification of a Cyanobacterial Membrane Protein with Amino Terminal Sequence Similarity to the N-Methylphenylalanine Pilins.

    1994 · 1 citations

64. Comparison of the contribution from different energy-linked reactions to the function of a membrane potential in photosynthetic bacteria

    1990 · 1 citations

65. ΔpH driven energy-linked NAD+ reduction in Rhodospirillum rubrum chromatophores

    1989 · 1 citations

66. Differential regulatory effects of the N-terminal region in SYK-fusion kinases reveal unique activation-inducible nuclear translocation of ITK-SYK

    2025 · 0 citations

67. Bacterial Open Reading Frame-112 Gene Expression induces Mammalian Cell Instability

    2024 · 0 citations

68. Formulation of Naturally Flavoured Mineral Water with Curcuma Longa

    2024 · 0 citations

69. Development of Halalan Tayyiban Plant-Based Cheese Formulations

    2024 · 0 citations

70. Exposure to Therapeutic BTK Inhibitors Induces Phenocopying of Btk29A Mutants in the Fruit Fly Drosophila melanogaster

    2023 · 0 citations

71. Estimation of Genetic Diversity in Four Genetic Groups of Local Kurdish Chicken Using RAPD-PCR

    2020 · 0 citations

72. BIOMARKER ASSESSMENT OF SERUM INTERLEUKIN-18 TOGETHER WITH HOMOCYSTEINE FOR POLYCYSTIC OVARIAN SYNDROME

    2019 · 0 citations

73. Pattern of Serum Irisin Hormone in Patients with Thyroid Dysfunction

    2019 · 0 citations

74. STATUS OF CIRCULATING SERUM TRYPTASE IN HEALTHY OBESE AND COMORBIDLY OBESE CONDITIONS

    2017 · 0 citations

75. Screening for a Single JAK2(p.V617F)Mutation Allele in Suspected Patients with Myeloproliferative Neoplasms (MPN) at HIWA Hospital

    2016 · 0 citations

76. Assessment on Elevated Serum Vitamin B 12 Level in Cancer Patients at Hiwa Hospital

    2016 · 0 citations

77. Sequence Verifications and Promoter Analysis of The Prolactin Gene

    2012 · 0 citations

78. INTRAMYOCARDIAL NONVIRAL GENE DELIVERY: THE IN VIVO EVALUATION OF TAT BASED PEPTIDES AS VECTORS FOR PLASMID DNA.

    2004 · 0 citations

79. Light-Driven Inorganic Pyrophosphate Synthesis in Phototrophic Bacteria

    1990 · 0 citations

80. Protonmotive coupling of energy conversion processes in photosyntetic bacteria : studies on membrane energization and photophosphorylation capacity

    1990 · 0 citations

81. Generation of Membrane Potential from Different Energy-Linked Reactions in Photosynthetic Bacteria

    1990 · 0 citations

82. Energy Coupling to Pyridine Nucleotide Transhydrogenase in Chromatophores from Phototrophic Bacteria

    1989 · 0 citations

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