Ken‐ichi Ito

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ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

1. Morphology of vulnerable coronary plaque: insights from follow-up of patients examined by intravascular ultrasound before an acute coronary syndrome

   2000 · 435 citations

2. Mutation of a Single Conserved Tryptophan in Multidrug Resistance Protein 1 (MRP1/ABCC1) Results in Loss of Drug Resistance and Selective Loss of Organic Anion Transport

   2001 · 166 citations

3. MEK–ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes

   2011 · 137 citations

4. Mutation of Trp1254 in the Multispecific Organic Anion Transporter, Multidrug Resistance Protein 2 (MRP2) (ABCC2), Alters Substrate Specificity and Results in Loss of Methotrexate Transport Activity

   2001 · 132 citations

5. Genetically engineered Bifidobacterium longum for tumor‐targeting enzyme‐prodrug therapy of autochthonous mammary tumors in rats

   2006 · 127 citations

6. Multimodality therapeutic outcomes In anaplastic thyroid carcinoma: Improved survival in subgroups of patients with localized primary tumors

   2011 · 115 citations

7. Randomized phase II study of concurrent versus sequential alternating gefitinib and chemotherapy in previously untreated non-small cell lung cancer with sensitive EGFR mutations: NEJ005/TCOG0902

   2015 · 110 citations

8. Augmentation of vessel squeezing at coronary-myocardial bridge by nitroglycerin: Study by quantitative coronary angiography and intravascular ultrasound

   1999 · 109 citations

9. A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance

   2002 · 107 citations

10. Idiopathic parkinsonism with superimposed manganese exposure: utility of positron emission tomography.

    1999 · 101 citations

11. Clinical significance of preoperative serum albumin level for prognosis in surgically resected patients with non-small cell lung cancer

    2017 · 99 citations

12. N‐Terminally extended human ubiquitin‐conjugating enzymes (E2s) mediate the ubiquitination of RING‐finger proteins, ARA54 and RNF8

    2001 · 98 citations

13. Increased Nuclear Localization of Transcription Factor Y-Box Binding Protein 1 Accompanied by Up-Regulation of P-glycoprotein in Breast Cancer Pretreated with Paclitaxel

    2005 · 93 citations

14. Endoscopic measurement of papillary sphincter zone and pancreatic main ductal pressure in patients with chronic pancreatitis

    1986 · 88 citations

15. Sorafenib in Japanese Patients with Locally Advanced or Metastatic Medullary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma

    2017 · 87 citations

16. 35th Annual Meeting of the European Association for the Study of Diabetes

    1999 · 86 citations

17. Chromoendoscopy with indigo carmine dye added to acetic acid in the diagnosis of gastric neoplasia: a prospective comparative study

    2008 · 80 citations

18. Runx3 is required for the differentiation of lung epithelial cells and suppression of lung cancer

    2010 · 77 citations

19. Suppression of Acute and Chronic Rejection by Hepatocyte Growth Factor in a Murine Model of Cardiac Transplantation

    2004 · 76 citations

20. RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

    2011 · 75 citations

21. A comparison of the end-tidal CO2 measured by portable capnometer and the arterial P CO2 in spontaneously breathing patients

    2003 · 68 citations

22. Astrocytes regulate ultra-slow arteriole oscillations via stretch-mediated TRPV4-COX-1 feedback

    2021 · 65 citations

23. Aberrant intracellular localization of RCAS1 is associated with tumor progression of gastric cancer

    2001 · 58 citations

24. Involvement of vascular endothelial growth factor and urokinase-type plasminogen activator receptor in microvessel invasion in human colorectal cancers

    1998 · 55 citations

25. Plaque Morphology at Coronary Sites With Focal Spasm in Variant Angina-Study Using Intravascular Ultrasound-

    2003 · 50 citations

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