RESEARCHER PROFILE

Donald J. Buchsbaum

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D

University of Alabama at Birmingham

Radiopharmaceutical Chemistry and ApplicationsMonoclonal and Polyclonal Antibodies ResearchPancreatic and Hepatic Oncology ResearchCell death mechanisms and regulationVirus-based gene therapy research

Donald J. Buchsbaum works in Radiopharmaceutical Chemistry and Applications, Monoclonal and Polyclonal Antibodies Research, Pancreatic and Hepatic Oncology Research, Cell death mechanisms and regulation, Virus-based gene therapy research. Recorded institutional associations include University of Alabama at Birmingham.

478Publications
11,745Citations
56H-index

ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

  1. The Wnt/β-catenin pathway in ovarian cancer: A review

    2013 · 457 citations

  2. Multi-targeted therapy of cancer by niclosamide: A new application for an old drug

    2014 · 364 citations

  3. Differential susceptibility of primary and established human glioma cells to adenovirus infection: targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer.

    1998 · 346 citations

  4. Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers.

    2000 · 218 citations

  5. 18F-2-deoxy-2-fluoro-D-glucose uptake into human tumor xenografts. Feasibility studies for cancer imaging with positron-emission tomography

    1991 · 214 citations

  6. The Small Heat Shock Protein αB-crystallin Is a Novel Inhibitor of TRAIL-induced Apoptosis That Suppresses the Activation of Caspase-3

    2005 · 209 citations

  7. A Targetable, Injectable Adenoviral Vector for Selective Gene Delivery to Pulmonary Endothelium in Vivo

    2000 · 203 citations

  8. Recurrent read-through fusion transcripts in breast cancer

    2014 · 181 citations

  9. Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes

    2016 · 169 citations

  10. ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines

    2013 · 164 citations

  11. The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype

    2016 · 164 citations

  12. Inhibition of Wnt/β-catenin pathway by niclosamide: A therapeutic target for ovarian cancer

    2014 · 161 citations

  13. Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway

    2003 · 159 citations

  14. Immunohistochemistry in the evaluation of neovascularization in tumor xenografts

    2008 · 158 citations

  15. Combined Modality Therapy of A431 Human Epidermoid Cancer Using Anti-EGFr Antibody C225 and Radiation

    1999 · 152 citations

  16. Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

    2011 · 147 citations

  17. Noninvasive monitoring of gene transfer using a reporter receptor imaged with a high-affinity peptide radiolabeled with 99mTc or 188Re.

    2000 · 144 citations

  18. Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model.

    2003 · 140 citations

  19. Rationales, evidence, and design considerations for fractionated radioimmunotherapy

    2002 · 129 citations

  20. An Adenovirus with Enhanced Infectivity Mediates Molecular Chemotherapy of Ovarian Cancer Cells and Allows Imaging of Gene Expression

    2001 · 125 citations

  21. Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas.

    2002 · 115 citations

  22. RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long‐term survival and reveals a role forANGPTL4

    2016 · 114 citations

  23. Polyethylene Glycosylated Curcumin Conjugate Inhibits Pancreatic Cancer Cell Growth through Inactivation of Jab1

    2009 · 113 citations

  24. Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation

    2002 · 111 citations

  25. Catalase Abrogates β-Lapachone–Induced PARP1 Hyperactivation–Directed Programmed Necrosis in NQO1-Positive Breast Cancers

    2013 · 101 citations

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