François Ghiringhelli

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ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

1. Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

   2017 · 5,611 citations

2. Calreticulin exposure dictates the immunogenicity of cancer cell death

   2006 · 3,198 citations

3. Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

   2007 · 3,043 citations

4. The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

   2013 · 2,044 citations

5. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

   2009 · 1,890 citations

6. Immunological aspects of cancer chemotherapy

   2007 · 1,707 citations

7. Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

   2005 · 1,509 citations

8. Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

   2011 · 1,373 citations

9. Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

   2006 · 1,241 citations

10. 5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell–Dependent Antitumor Immunity

    2010 · 1,239 citations

11. Immunogenic death of colon cancer cells treated with oxaliplatin

    2009 · 1,173 citations

12. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

    2010 · 998 citations

13. CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

    2005 · 949 citations

14. CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

    2004 · 880 citations

15. Consensus guidelines for the detection of immunogenic cell death

    2014 · 831 citations

16. Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4 + CD25 + regulatory T cell proliferation

    2005 · 776 citations

17. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

    2012 · 774 citations

18. Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer

    2022 · 677 citations

19. The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

    2007 · 574 citations

20. The anticancer immune response: indispensable for therapeutic success?

    2008 · 573 citations

21. Molecular characteristics of immunogenic cancer cell death

    2007 · 494 citations

22. Classification of current anticancer immunotherapies

    2014 · 468 citations

23. An Immunosurveillance Mechanism Controls Cancer Cell Ploidy

    2012 · 435 citations

24. Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

    2012 · 423 citations

25. A novel dendritic cell subset involved in tumor immunosurveillance

    2006 · 405 citations

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