RESEARCHER PROFILE
Horacio Pérez‐Sánchez
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Universidad Católica de Murcia
Horacio Pérez‐Sánchez works in Computational Drug Discovery Methods, Protein Structure and Dynamics, Cholinesterase and Neurodegenerative Diseases, Parallel Computing and Optimization Techniques, Machine Learning in Materials Science. Recorded institutional associations include Universidad Católica de Murcia.
330Publications
6,041Citations
38H-index
Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.
Selected research works
Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.
MCC950 closes the active conformation of NLRP3 to an inactive state
2019 · 439 citationsNeural network and deep-learning algorithms used in QSAR studies: merits and drawbacks
2018 · 224 citationsHigh-Throughput parallel blind Virtual Screening using BINDSURF
2012 · 190 citationsA Comprehensive Docking and MM/GBSA Rescoring Study of Ligand Recognition upon Binding Antithrombin
2017 · 190 citationsManaging, Analysing, and Integrating Big Data in Medical Bioinformatics: Open Problems and Future Perspectives
2014 · 173 citationsAutomatic selection of molecular descriptors using random forest: Application to drug discovery
2016 · 157 citationsApplication advances of deep learning methods for de novo drug design and molecular dynamics simulation
2021 · 155 citationsStructure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo
2017 · 128 citationsEvaluation of the Anti-Diabetic Activity of Some Common Herbs and Spices: Providing New Insights with Inverse Virtual Screening
2019 · 109 citationsDeep neural network in QSAR studies using deep belief network
2017 · 104 citationsCuminaldehyde as the Major Component of Cuminum cyminum , a Natural Aldehyde with Inhibitory Effect on Alpha‐Synuclein Fibrillation and Cytotoxicity
2015 · 101 citationsA Review of Ligand-Based Virtual Screening Web Tools and Screening Algorithms in Large Molecular Databases in the Age of Big Data
2018 · 96 citationsEffect of inclusion of hydroxycinnamic and chlorogenic acids from green coffee bean in β-cyclodextrin on their interactions with whey, egg white and soy protein isolates
2014 · 88 citationsAccelerating Big Data Analysis through LASSO-Random Forest Algorithm in QSAR Studies
2021 · 77 citationsTowards the Interpretability of Machine Learning Predictions for Medical Applications Targeting Personalised Therapies: A Cancer Case Survey
2021 · 71 citationsChitosan as stabilizing agent for negatively charged nanoparticles
2016 · 68 citationsSelective in vitro and in silico butyrylcholinesterase inhibitory activity of diterpenes and rosmarinic acid isolated from Perovskia atriplicifolia Benth. and Salvia glutinosa L.
2016 · 65 citationsNew arylated benzo[h]quinolines induce anti-cancer activity by oxidative stress-mediated DNA damage
2016 · 64 citationsNew role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells
2020 · 64 citationsStructure guided design and binding analysis of EGFR inhibiting analogues of erlotinib and AEE788 using ensemble docking, molecular dynamics and MM-GBSA
2016 · 60 citationsUse of cyclodextrins to recover catechin and epicatechin from red grape pomace
2016 · 57 citationsIntermolecular Carbonyl–olefin Metathesis with Vinyl Ethers Catalyzed by Homogeneous and Solid Acids in Flow
2019 · 57 citationsHepatoprotective activity of chrysin is mediated through TNF-α in chemically-induced acute liver damage: An in vivo study and molecular modeling
2017 · 55 citationsHantzsch-Type Dihydropyridines and Biginelli-Type Tetra-hydropyrimidines: A Review of their Chemotherapeutic Activities
2015 · 53 citationsThe FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo
2021 · 52 citations