RESEARCHER PROFILE

Gerd Geißlinger

← Back to Goethe University Frankfurt

G

Goethe University Frankfurt

Pain Mechanisms and TreatmentsInflammatory mediators and NSAID effectsPharmacogenetics and Drug MetabolismSphingolipid Metabolism and SignalingIon Channels and Receptors

Gerd Geißlinger works in Pain Mechanisms and Treatments, Inflammatory mediators and NSAID effects, Pharmacogenetics and Drug Metabolism, Sphingolipid Metabolism and Signaling, Ion Channels and Receptors. Recorded institutional associations include Goethe University Frankfurt, Fraunhofer Institute for Translational Medicine and Pharmacology, Fraunhofer-Gesellschaft.

751Publications
32,413Citations
87H-index

ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

  1. Cyclooxygenase‐independent actions of cyclooxygenase inhibitors

    2001 · 747 citations

  2. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

    2006 · 548 citations

  3. COX‐2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX‐2 inhibitor celecoxib

    2001 · 501 citations

  4. Chain length-specific properties of ceramides

    2011 · 483 citations

  5. Cyclooxygenase-2 (COX-2)–Independent Anticarcinogenic Effects of Selective COX-2 Inhibitors

    2006 · 480 citations

  6. Ziconotide for treatment of severe chronic pain

    2010 · 356 citations

  7. Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain

    2014 · 344 citations

  8. Up‐regulation of cyclooxygenase‐2 mRNA in the rat spinal cord following peripheral inflammation

    1996 · 329 citations

  9. Pharmacokinetics of Opioids in Liver Disease

    1999 · 306 citations

  10. Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer

    2007 · 302 citations

  11. COX-dependent mechanisms involved in the antinociceptive action of NSAIDs at central and peripheral sites

    2005 · 259 citations

  12. Genetic Predictors of the Clinical Response to Opioid Analgesics

    2004 · 256 citations

  13. The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

    2022 · 229 citations

  14. Analgesic effects of morphine and morphine‐6‐glucuronide in a transcutaneous electrical pain model in healthy volunteers

    2003 · 226 citations

  15. Ceramide synthases and ceramide levels are increased in breast cancer tissue

    2009 · 225 citations

  16. Capturing adenylyl cyclases as potential drug targets

    2009 · 224 citations

  17. The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine

    2002 · 211 citations

  18. Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth

    2012 · 209 citations

  19. The IKK‐NF‐κB pathway: a source for novel molecular drug targets in pain therapy?

    2008 · 209 citations

  20. Opioids As Modulators of Cell Death and Survival—Unraveling Mechanisms and Revealing New Indications

    2004 · 204 citations

  21. Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?

    2022 · 196 citations

  22. THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro

    2017 · 192 citations

  23. Ceramides as Novel Disease Biomarkers

    2018 · 188 citations

  24. No NO, no pain? The role of nitric oxide and cGMP in spinal pain processing

    2009 · 187 citations

  25. SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

    2016 · 177 citations

← Return to the university profile