Jan‐Henning Klusmann

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ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

1. Childhood obesity: increased risk for cardiometabolic disease and cancer in adulthood

   2018 · 566 citations

2. lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

   2017 · 423 citations

3. Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study

   2016 · 330 citations

4. Developmental stage–selective effect of somatically mutated leukemogenic transcription factor GATA1

   2005 · 305 citations

5. Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications

   2017 · 293 citations

6. The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

   2021 · 262 citations

7. Treatment and prognostic impact of transient leukemia in neonates with Down syndrome

   2008 · 258 citations

8. Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012

   2018 · 254 citations

9. miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia

   2010 · 220 citations

10. The non-coding RNA landscape of human hematopoiesis and leukemia

    2017 · 157 citations

11. miR-99a/100∼125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling

    2014 · 156 citations

12. LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia

    2014 · 154 citations

13. Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

    2019 · 143 citations

14. Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis

    2010 · 140 citations

15. Next‐generation sequencing for minimal residual disease monitoring in acute myeloid leukemia patients with FLT3 ‐ITD or NPM1 mutations

    2012 · 133 citations

16. Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

    2013 · 121 citations

17. Analysis of GATA1 mutations in Down syndrome transient myeloproliferative disorder and myeloid leukemia

    2011 · 112 citations

18. The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells

    2011 · 103 citations

19. Lost in translation: pluripotent stem cell‐derived hematopoiesis

    2015 · 99 citations

20. Childhood Obesity and Cancer Risk in Adulthood

    2020 · 95 citations

21. Therapy reduction in patients with Down syndrome and myeloid leukemia: the international ML-DS 2006 trial

    2017 · 93 citations

22. CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells

    2024 · 90 citations

23. miR-9 is a tumor suppressor in pediatric AML with t(8;21)

    2013 · 89 citations

24. Prevalence and prognostic value of IDH1 and IDH2 mutations in childhood AML: a study of the AML–BFM and DCOG study groups

    2011 · 85 citations

25. The role of matched sibling donor allogeneic stem cell transplantation in pediatric high-risk acute myeloid leukemia: results from the AML-BFM 98 study

    2011 · 82 citations

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