RESEARCHER PROFILE

Federico Buonanno

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F

University of Macerata

Protist diversity and phylogenyMicrobial Natural Products and BiosynthesisMarine Sponges and Natural ProductsEnvironmental Toxicology and EcotoxicologyBioactive Compounds and Antitumor Agents

Federico Buonanno works in Protist diversity and phylogeny, Microbial Natural Products and Biosynthesis, Marine Sponges and Natural Products, Environmental Toxicology and Ecotoxicology, Bioactive Compounds and Antitumor Agents. Recorded institutional associations include University of Macerata.

116Publications
776Citations
18H-index

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

  1. Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells

    2018 · 65 citations
  2. Biomonitoring of Lake Garda: Identification of ciliate species and symbiotic algae responsible for the “black-spot” bloom during the summer of 2004

    2008 · 56 citations
  3. Natural products from aquatic eukaryotic microorganisms for cancer therapy: Perspectives on anti-tumour properties of ciliate bioactive molecules

    2016 · 48 citations
  4. Chemical defence by means of extrusive cortical granules in the heterotrich ciliate Climacostomum virens

    2003 · 46 citations
  5. Climacostol reduces tumour progression in a mouse model of melanoma via the p53-dependent intrinsic apoptotic programme

    2016 · 44 citations
  6. The protozoan toxin climacostol inhibits growth and induces apoptosis of human tumor cell lines

    2008 · 41 citations
  7. The Natural Compound Climacostol as a Prodrug Strategy Based on pH Activation for Efficient Delivery of Cytotoxic Small Agents

    2019 · 41 citations
  8. Chemical Offense by Means of Toxicysts in the Freshwater Ciliate, Coleps hirtus

    2014 · 33 citations
  9. Climacostol, a defense toxin of Climacostomum virens (protozoa, ciliata), and its congeners

    2004 · 31 citations
  10. Antimicrobial activity of the protozoan toxin climacostol and its derivatives

    2012 · 28 citations
  11. Chemical defence by mono-prenyl hydroquinone in a freshwater ciliate, Spirostomum ambiguum

    2011 · 25 citations
  12. Defence function of pigmentocysts in the karyorelictid ciliate Loxodes striatus

    2005 · 24 citations
  13. DNA binding and oxidative DNA damage induced by climacostol–copper(II) complexes: Implications for anticancer properties

    2013 · 23 citations
  14. The Defensive Function of Trichocysts inParamecium tetraureliaAgainst Metazoan Predators Compared with the Chemical Defense of Two Species of Toxin-containing Ciliates

    2013 · 23 citations
  15. The protozoan toxin climacostol and its derivatives: Cytotoxicity studies on 10 species of free-living ciliates

    2010 · 21 citations
  16. Variations in the efficiency of ciliate extrusomal toxins against a common ciliate predator, the catenulid Stenostomum Sphagnetorum

    2005 · 21 citations
  17. A Straightforward Diastereoselective Synthesis and Evaluation of Climacostol, A Natural Product with Anticancer Activities

    2010 · 19 citations
  18. A re-description of the ciliate genus and type species, Balantidium entozoon

    2009 · 19 citations
  19. The changes in the predatory behavior of the microturbellarian Stenostomum sphagnetorum on two species of toxin-secreting ciliates of the genus Spirostomum

    2011 · 18 citations
  20. Metabolites from the Euryhaline Ciliate Pseudokeronopsis erythrina

    2016 · 15 citations
  21. Bioactive molecules from protists: Perspectives in biotechnology

    2020 · 14 citations
  22. Antipredator Behavior of the Freshwater MicroturbellarianStenostomum sphagnetorumAgainst the Predatory CiliateDileptus margaritifer

    2009 · 13 citations
  23. Chemical Defense by Erythrolactones in the Euryhaline Ciliated Protist,Pseudokeronopsis erythrina

    2017 · 12 citations
  24. Cell aging-induced methionine oxidation causes an autocrine to paracrine shift of the pheromone activity in the protozoan ciliate, Euplotes raikovi

    2011 · 9 citations
  25. Bioactivity and Structural Properties of Novel Synthetic Analogues of the Protozoan Toxin Climacostol

    2019 · 9 citations

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