RESEARCHER PROFILE

Laura Daniela Alaniz

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National University of Northwestern Buenos Aires

Proteoglycans and glycosaminoglycans researchImmunotherapy and Immune ResponsesHydrogels: synthesis, properties, applicationsCancer Cells and MetastasisLiver physiology and pathology

Laura Daniela Alaniz works in Proteoglycans and glycosaminoglycans research, Immunotherapy and Immune Responses, Hydrogels: synthesis, properties, applications, Cancer Cells and Metastasis, Liver physiology and pathology. Recorded institutional associations include Consejo Nacional de Investigaciones Científicas y Técnicas, National University of Northwestern Buenos Aires, Universidad Nacional de San Antonio de Areco.

89Publications
2,021Citations
28H-index

ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

  1. Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance

    2019 · 118 citations

  2. Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice

    2011 · 98 citations

  3. Inhibition of NF-κB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines

    2005 · 90 citations

  4. Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P‐glycoprotein activity and PI3K/Akt pathway

    2007 · 83 citations

  5. Mesenchymal Stromal Cells Engineered to Produce IGF-I by Recombinant Adenovirus Ameliorate Liver Fibrosis in Mice

    2014 · 79 citations

  6. PI3K/Akt inhibition modulates multidrug resistance and activates NF-κB in murine lymphoma cell lines

    2008 · 77 citations

  7. Hepatocellular Carcinoma Cells and Their Fibrotic Microenvironment Modulate Bone Marrow-Derived Mesenchymal Stromal Cell Migration in Vitro and in Vivo

    2011 · 64 citations

  8. Low molecular weight hyaluronan inhibits colorectal carcinoma growth by decreasing tumor cell proliferation and stimulating immune response

    2009 · 59 citations

  9. Adenovirus‐mediated inhibition of SPARC attenuates liver fibrosis in rats

    2008 · 58 citations

  10. Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-κB and expression of the long-noncoding RNA HAS2–AS1

    2020 · 56 citations

  11. 4-Methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis

    2015 · 54 citations

  12. Interaction of CD44 with Different Forms of Hyaluronic Acid. Its Role in Adhesion and Migration of Tumor Cells

    2002 · 53 citations

  13. Lack of the Matricellular Protein SPARC (Secreted Protein, Acidic and Rich in Cysteine) Attenuates Liver Fibrogenesis in Mice

    2013 · 51 citations

  14. Increased Migration of Human Mesenchymal Stromal Cells by Autocrine Motility Factor (AMF) Resulted in Enhanced Recruitment towards Hepatocellular Carcinoma

    2014 · 50 citations

  15. The immunological effect of hyaluronan in tumor angiogenesis

    2015 · 50 citations

  16. Hyaluronan in the Tumor Microenvironment

    2020 · 50 citations

  17. Targeting the Tumor Extracellular Matrix by the Natural Molecule 4-Methylumbelliferone: A Complementary and Alternative Cancer Therapeutic Strategy

    2021 · 45 citations

  18. A Novel Synergistic Combination of Cyclophosphamide and Gene Transfer of Interleukin-12 Eradicates Colorectal Carcinoma in Mice

    2009 · 44 citations

  19. Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells

    2009 · 43 citations

  20. SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1and PDGF

    2011 · 41 citations

  21. Hyaluronan preconditioning of monocytes/macrophages affects their angiogenic behavior and regulation of TSG ‐6 expression in a tumor type‐specific manner

    2019 · 38 citations

  22. Role of Hyaluronic acid and its chemical derivatives in immunity during homeostasis, cancer and tissue regeneration

    2024 · 38 citations

  23. Modulation of matrix metalloproteinase-9 activity by hyaluronan is dependent on NF-κB activity in lymphoma cell lines with dissimilar invasive behavior

    2004 · 35 citations

  24. Reversal of gastrointestinal carcinoma‐induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL‐12

    2011 · 33 citations

  25. Hyaluronan oligosaccharides induce cell death through PI3-K/Akt pathway independently of NF-κB transcription factor

    2006 · 32 citations

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