Jan Steyaert
← Back to Vrije Universiteit Brussel
Vrije Universiteit Brussel
Jan Steyaert works in Enzyme Structure and Function, Protein Structure and Dynamics, Receptor Mechanisms and Signaling, Monoclonal and Polyclonal Antibodies Research, Neuroscience and Neuropharmacology Research. Recorded institutional associations include Vrije Universiteit Brussel, Vlaams Instituut voor Biotechnologie, VIB-VUB Center for Structural Biology.
Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.
Selected research works
Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 · 3,002 citationsStructure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 · 1,680 citationsActivation and allosteric modulation of a muscarinic acetylcholine receptor
2013 · 893 citationsStructural insights into µ-opioid receptor activation
2015 · 885 citationsConformational biosensors reveal GPCR signalling from endosomes
2013 · 818 citationsA general protocol for the generation of Nanobodies for structural biology
2014 · 790 citationsGABAA receptor signalling mechanisms revealed by structural pharmacology
2018 · 551 citationsDistinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis
2017 · 379 citationsStructure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor
2018 · 365 citationsAllosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
2016 · 330 citationsGABAA receptor signalling mechanisms revealed by structural pharmacology.
2019 · 330 citationsStructural insights into the activation of metabotropic glutamate receptors
2019 · 325 citationsThe Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier
2019 · 319 citationsCryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer
2018 · 314 citationsAllosteric coupling from G protein to the agonist-binding pocket in GPCRs
2016 · 290 citationsA Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action
2018 · 286 citationsNanobodies to Study G Protein–Coupled Receptor Structure and Function
2016 · 257 citationsStructures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
2013 · 256 citationsPropagation of conformational changes during μ-opioid receptor activation
2015 · 255 citationsStructure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes
2015 · 245 citationsStructural flexibility of the Gαs α-helical domain in the β 2 -adrenoceptor Gs complex
2011 · 235 citationsNanobody stabilization of G protein-coupled receptor conformational states
2011 · 234 citationsStructures of β-klotho reveal a ‘zip code’-like mechanism for endocrine FGF signalling
2018 · 232 citationsStructures of influenza A virus RNA polymerase offer insight into viral genome replication
2019 · 231 citationsStructure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex
2019 · 220 citations